BDBM414044 2-{1-[(7R)-6-{6-chloro- 1H-pyrrolo[2,3-b]pyridin- 4-yl}-7-methyl- 5H,6H,7H,8H-pyrido[4,3- d]pyrimidin-4- yl]azetidin-3-yl}propan- 2-ol::US10421765, Example 33::US10745420, Example 33

SMILES C[C@@H]1Cc2ncnc(N3CC(C3)C(C)(C)O)c2CN1c1cc(Cl)nc2[nH]ccc12

InChI Key InChIKey=OUQSYGXJWVZANH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414044   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM414044(US10421765, Example 33 | 2-{1-[(7R)-6-{6-chloro- 1...)
Affinity DataIC50: 183nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM414044(US10421765, Example 33 | 2-{1-[(7R)-6-{6-chloro- 1...)
Affinity DataIC50: 183nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent