BDBM4137 (2S,4S)-N-tert-butyl-4-chloro-1-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-4-(4-hydroxyphenyl)butanoyl]pyrrolidine-2-carboxamide::(3-Hydroxy-2-methylbenzoyl)-{2(S)-hydroxy-3(S)-amino-4-(4-hydroxy)-phenylbutanoyl}-4(S)-Cl-Pro-NH-t-Bu::AHPBA deriv. 22

SMILES Cc1c(O)cccc1C(=O)N[C@@H](Cc1ccc(O)cc1)[C@H](O)C(=O)N1C[C@@H](Cl)C[C@H]1C(=O)NC(C)(C)C

InChI Key InChIKey=BORBJWKYKJPMOQ-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4137   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4137((2S,4S)-N-tert-butyl-4-chloro-1-[(2S,3S)-2-hydroxy...)
Affinity DataIC50: 1.30nMAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
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Date in BDB:
4/29/2005
Entry Details Article
PubMed