BDBM413590 (2S)-2-[[(2S)-1-acetylpyrrolidine-2-carbonyl]-methyl-amino]-N-[(1S)-2-(hydroxyamino)-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]pentanediamide::US10414797, Comparative Example 20::US10414797, Example C20
SMILES CN([C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NO)C(=O)[C@@H]1CCCN1C(C)=O
InChI Key InChIKey=JEUOYAXZEUGPRO-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 413590
Affinity DataIC50: 5.30E+4nMAssay Description:MMP-2: Recombinant MMP-2 expressed in Chinese hamster ovary (CHO) cells was obtained from Merck-Millipore (catalog number PF023-5UG). DQ gelatin from...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 2.20E+4nMAssay Description:MMP-9: Recombinant MMP-9 expressed was obtained from Merck-Millipore (catalog number PF140-5UG, used in examples 1 to 9 and comparative examples) and...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 2.00E+6nMAssay Description:MMP-1:MMP-1 peptide substrate was provided as a stock solution in DMSO (6 mM). For the assay, the substrate was diluted 1× reaction buffer to a conce...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 2.00E+6nMAssay Description:MMP-3: Preparation of the MMP-3 for the activity assay: MMP-3 was provided as a stock solution (0.1 mg/mL). The enzyme was diluted in water to a fina...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 2.00E+6nMAssay Description:MMP-7: Recombinant MMP-7 expressed in E. Coli was obtained from Merck-Millipore (catalog number 44270). Mca-PLGL-Dpa-AR-NH2 (fluorogenic peptide subs...More data for this Ligand-Target Pair
Ligand InfoSimilars