BDBM413461 O-[4-({2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-[(2S)-tetrahydro-2H-pyran-2-yl]propanoyl}amino)benzoyl]-L-threonine (Enantiomerically Pure Diastereomer)::US10414731, Example 1

SMILES COc1cn(C(C[C@@H]2CCCCO2)C(=O)Nc2ccc(cc2)C(=O)OC(C)[C@H](N)C(O)=O)c(=O)cc1-c1cc(Cl)ccc1C#N

InChI Key InChIKey=RJCKFKUUPUIXCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413461   

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM413461(O-[4-({2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-o...)
Affinity DataIC50: 2nMAssay Description:Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting final con...More data for this Ligand-Target Pair
Ligand InfoKEGGSimilars
In Depth
Date in BDB:
8/2/2020
Entry Details
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