BDBM413395 US10407423, Compound 2-02

SMILES Cc1ccc(o1)-c1nc2cc(OCCCN3CCCC3)ccc2c2NCCCc12

InChI Key InChIKey=FCNUPLHGDZARAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 413395   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
FundaciÓN Para La InvestigaciÓN MÉDica Aplicada

US Patent
LigandPNGBDBM413395(US10407423, Compound 2-02)
Affinity DataIC50: 5.50E+3nMAssay Description:The biochemical assay to measure G9a enzyme activity relies on time-resolved fluorescence energy transfer (TR-FRET) between europium cryptate (donor)...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetDNA (cytosine-5)-methyltransferase 1(Human)
FundaciÓN Para La InvestigaciÓN MÉDica Aplicada

US Patent
LigandPNGBDBM413395(US10407423, Compound 2-02)
Affinity DataIC50: 750nMAssay Description:The biochemical assay to measure DNMT1 enzyme activity relies on time-resolved fluorescence energy transfer (TR-FRET) between lumi4-Tb (donor) and d2...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent