BDBM4125 (2S,4S)-N-tert-butyl-4-chloro-1-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-4-(4-methylphenyl)butanoyl]pyrrolidine-2-carboxamide::(3-Hydroxy-2-methylbenzoyl)-(2(S)-hydroxy-3(S)-amino-4-p-tolylbutanoyl)-4(S)-Cl-Pro-NH-t-Bu::AHPBA deriv. 10

SMILES Cc1ccc(C[C@H](NC(=O)c2cccc(O)c2C)[C@H](O)C(=O)N2C[C@@H](Cl)C[C@H]2C(=O)NC(C)(C)C)cc1

InChI Key InChIKey=RLZKHQBPOHJKGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4125   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4125((3-Hydroxy-2-methylbenzoyl)-(2(S)-hydroxy-3(S)-ami...)
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2005
Entry Details Article
PubMed