BDBM412340 US10399958, Compound 2e

SMILES C\C(CCC(O)=O)=C/COc1ccccc1Cn1c(C)cnc1-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=LKBNNCNNGBRSKP-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 412340   

TargetPeroxisome proliferator-activated receptor delta(Human)
Mitobridge

US Patent
LigandPNGBDBM412340(US10399958, Compound 2e)
Affinity DataEC50:  0.200nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Mitobridge

US Patent
LigandPNGBDBM412340(US10399958, Compound 2e)
Affinity DataEC50:  0.300nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM412340(US10399958, Compound 2e)
Affinity DataEC50:  2.29E+3nMAssay Description:Modulator activity at GAL4-fused human PPARalpha LBD (unknown origin) transfected in African green monkey CV1 cells assessed as receptor transactivat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM412340(US10399958, Compound 2e)
Affinity DataEC50: >1.00E+4nMAssay Description:Modulator activity at GAL4-fused human PPARgamma LBD (unknown origin) transfected in African green monkey CV1 cells assessed as receptor transactivat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed