BDBM4123 (2S,4S)-N-tert-butyl-4-chloro-1-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-5-phenylpentanoyl]pyrrolidine-2-carboxamide::(3-Hydroxy-2-methylbenzoyl)-(2(S)-hydroxy-3(S)-amino-5-phenylpentanoyl)-4(S)-Cl-Pro-NH-t-Bu::AHPPA deriv. 8

SMILES Cc1c(O)cccc1C(=O)N[C@@H](CCc1ccccc1)[C@H](O)C(=O)N1C[C@@H](Cl)C[C@H]1C(=O)NC(C)(C)C

InChI Key InChIKey=ZDOFSOVSNDBLFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4123   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4123((3-Hydroxy-2-methylbenzoyl)-(2(S)-hydroxy-3(S)-ami...)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed