BDBM412266 US10399945, Example 18::US10399945, Example 5::US10669239, Compound 5::US10927079, Compound 18

SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cn[nH]c1)-c1ccccc1

InChI Key InChIKey=ANPABKZOHMECMC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 412266   

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412266(US10399945, Example 18 | US10399945, Example 5 | U...)
Affinity DataIC50: 50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412266(US10399945, Example 18 | US10399945, Example 5 | U...)
Affinity DataIC50: 50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412266(US10399945, Example 18 | US10399945, Example 5 | U...)
Affinity DataIC50: 50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412266(US10399945, Example 18 | US10399945, Example 5 | U...)
Affinity DataIC50: 0.100nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412266(US10399945, Example 18 | US10399945, Example 5 | U...)
Affinity DataIC50: 0.100nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent