BDBM410294 (rac)-N-(4-methyl-3-(2,4,4a,6-tetrahydro-1H-spiro[[1,4]oxazino[4,3-a]quinoline-5,3′-oxetan]-9-yl)phenyl)-2-(trifluoromethyl)isonicotinamide::US10377770, Example 54

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1ccc2CC3(COC3)C3COCCN3c2c1

InChI Key InChIKey=LCUYDFYMIZYCJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410294   

LigandPNGBDBM410294((rac)-N-(4-methyl-3-(2,4,4a,6-tetrahydro-1H-spiro[...)
Affinity DataIC50: 0.0130nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
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