BDBM410273 2-(1,1-difluoroethyl)-N-(3-(6-methoxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl)isonicotinamide::US10377770, Example 36

SMILES CO[C@H]1C[C@H]2COCCN2c2cc(cnc12)-c1cc(NC(=O)c2ccnc(c2)C(C)(F)F)ccc1C

InChI Key InChIKey=YFRDIEDZKKVLFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410273   

LigandPNGBDBM410273(2-(1,1-difluoroethyl)-N-(3-(6-methoxy-1,2,4,4a,5,6...)
Affinity DataIC50: 0.0130nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
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