BDBM410174 US10370375, Example 22

SMILES CNS(=O)(=O)C[C@H]1CCC(CC1)n1cnc2cnc3[nH]ccc3c12

InChI Key InChIKey=IOJYFDLNTJHKIW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 410174   

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410174(US10370375, Example 22)
Affinity DataIC50: 10nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410174(US10370375, Example 22)
Affinity DataIC50: 260nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410174(US10370375, Example 22)
Affinity DataIC50: 130nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In DepthDetails
US Patent