BDBM40974 (3Z)-3-[(3,4-dimethoxyanilino)methylene]oxindole::(3Z)-3-[(3,4-dimethoxyanilino)methylidene]-1H-indol-2-one::(3Z)-3-[[(3,4-dimethoxyphenyl)amino]methylidene]-1H-indol-2-one::(3Z)-3-{[(3,4-dimethoxyphenyl)amino]methylene}-1,3-dihydro-2H-indol-2-one::MLS000043274::SMR000019894::cid_5771508

SMILES COc1ccc(cc1OC)N=CC1C(=O)Nc2ccccc12

InChI Key InChIKey=CDQXCUQMYDDRNG-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 40974   

TargetFocal adhesion kinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40974(cid_5771508 | (3Z)-3-[[(3,4-dimethoxyphenyl)amino]...)
Affinity DataIC50: 1.97E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2011
Entry Details
PCBioAssay
TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40974(cid_5771508 | (3Z)-3-[[(3,4-dimethoxyphenyl)amino]...)
Affinity DataIC50: 9.31E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetProtein-tyrosine kinase 2-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40974(cid_5771508 | (3Z)-3-[[(3,4-dimethoxyphenyl)amino]...)
Affinity DataIC50: 3.78E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase 33(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM40974(cid_5771508 | (3Z)-3-[[(3,4-dimethoxyphenyl)amino]...)
Affinity DataEC50:  5.22E+3nMAssay Description:Keywords: STK33 Kinase, Non-ATP Competitive Inhibitor Assay Overview: Purified STK33 Kinase is preincubated with potential inhibitors and allowed to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay