BDBM406376 2-((3,4-trans)-4-Hydroxy-3-(pyridin-2-ylmethyl)chroman-7-yl)-N-(neopentylsulfonyl)benzamide::US10336733, Example 20

SMILES CC(C)(C)CS(=O)(=O)NC(=O)c1ccccc1-c1ccc2C(O)C(Cc3ccccn3)COc2c1

InChI Key InChIKey=ZMICREPXROYQSV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406376   

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandPNGBDBM406376(2-((3,4-trans)-4-Hydroxy-3-(pyridin-2-ylmethyl)chr...)
Affinity DataEC50:  44nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In DepthDetails
US Patent