BDBM403473 (R)- or (S)-2- ((difluoro- methoxy)methyl)- 5-(4- fluorophenyl)- 3,4-dihydro-2H- pyrano[2,3- b]pyridine-7- carboxamide::US10335399, Example 3-2B::US10806724, Example 3-2B

SMILES NC(=O)c1cc(-c2ccc(F)cc2)c2CC[C@@H](COC(F)F)Oc2n1

InChI Key InChIKey=LCYHJVAJRLFZEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403473   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM403473(US10335399, Example 3-2B | (R)- or (S)-2- ((difluo...)
Affinity DataIC50: 86nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
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TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM403473(US10335399, Example 3-2B | (R)- or (S)-2- ((difluo...)
Affinity DataIC50: 86nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent