BDBM403440 (6S,9R)- or (6R,9S)- 4-(4-chloro-2- fluorophenyl)-6,7,8,9- tetrahydro-5H-6,9- epoxycyclo- hepta[b]pyridine-2- carboxamide::US10335399, Example 1-3A::US10806724, Example 1-3A

SMILES NC(=O)c1cc(c2[C@H]3CC[C@H](O3)c2n1)-c1ccc(Cl)cc1F

InChI Key InChIKey=FJXVLWXBRGYNDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403440   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM403440(US10335399, Example 1-3A | (6S,9R)- or (6R,9S)- 4-...)
Affinity DataIC50: 65nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM403440(US10335399, Example 1-3A | (6S,9R)- or (6R,9S)- 4-...)
Affinity DataIC50: 65nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent