BDBM403438 US10335399, Example 1-2A::US10806724, Example 1-2A

SMILES NC(=O)c1cc(c2C[C@@H]3CC[C@@H](O3)c2n1)-c1ccc(F)cc1F

InChI Key InChIKey=MTMLJAALOFBSKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403438   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM403438(US10335399, Example 1-2A | US10806724, Example 1-2...)
Affinity DataIC50: 376nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM403438(US10335399, Example 1-2A | US10806724, Example 1-2...)
Affinity DataIC50: 376nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent