BDBM402839 2-[(3S)-3-aminopiperidin- 1-yl]-N-(2-cyanothiophen- 3-yl)pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10329295, Example 152

SMILES N[C@H]1CCCN(C1)c1ncc2ccc(C(=O)Nc3ccsc3C#N)n2n1

InChI Key InChIKey=YSTFQQIDRPIVOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402839   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402839(US10329295, Example 152 | 2-[(3S)-3-aminopiperidin...)
Affinity DataIC50: 7nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
Go to US Patent