BDBM4024 2-{[1,5-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1,5-dimethyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10i

SMILES Cc1ccc2n(C)c(SSc3c(C(=O)Nc4ccccc4)c4cc(C)ccc4n3C)c(C(=O)Nc3ccccc3)c2c1

InChI Key InChIKey=TUPADNGSOVYYFT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4024   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4024(2-{[1,5-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
University of Auckland

LigandPNGBDBM4024(2-{[1,5-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4024(2-{[1,5-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed