BDBM402330 US10329282, Compound TDI01176::US11390609, Compound TDI01176

SMILES CC(CO)NC(=O)c1cc2ccc(cc2[nH]1)-c1nccc(Nc2ccc3[nH]ncc3c2)n1

InChI Key InChIKey=BBXXHBWFOCUGJH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 402330   

TargetRho-associated protein kinase 2 [1-119](Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402330(US10329282, Compound TDI01176 | US11390609, Compou...)
Affinity DataIC50: 28nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402330(US10329282, Compound TDI01176 | US11390609, Compou...)
Affinity DataIC50: 521nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402330(US10329282, Compound TDI01176 | US11390609, Compou...)
Affinity DataIC50: 28nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In DepthDetails
US Patent