BDBM402284 (N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)methyl)benzamide)::US10011611, RBC-3001-A

SMILES ONC(=O)c1ccc(Cn2sc3ncccc3c2=O)cc1

InChI Key InChIKey=VLJAVCKTTLIBDT-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 402284   

TargetHistone deacetylase 1(Human)
Reaction Biology

US Patent
LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 175nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
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TargetHistone deacetylase 2(Human)
Reaction Biology

US Patent
LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 5.40E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 1.31E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 4 [627-1085](Human)
Reaction Biology

US Patent
LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 3.31E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 5(Human)
Reaction Biology

US Patent
LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 508nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Reaction Biology

US Patent
LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 0.958nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 7 [518-592](Human)
Reaction Biology

US Patent
LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 1.89E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Reaction Biology

US Patent
LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 27.1nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 9 [604-1066](Human)
Reaction Biology

US Patent
LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 1.41E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Reaction Biology

US Patent
LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 4.26E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 11(Human)
Reaction Biology

US Patent
LigandPNGBDBM402284(US10011611, RBC-3001-A | (N-hydroxy-4-((3-oxoisoth...)
Affinity DataIC50: 2.84E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent