BDBM401033 US10005735, Compound 31

SMILES Sc1cccc2cc(cnc12)C(=O)NCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12

InChI Key InChIKey=HYFDMCAGFXUWQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 401033   

Target26S proteasome non-ATPase regulatory subunit 14(Human)
California Institute of Technology

US Patent
LigandPNGBDBM401033(US10005735, Compound 31)
Affinity DataIC50: 200nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCOP9 signalosome complex subunit 5(Human)
California Institute of Technology

US Patent
LigandPNGBDBM401033(US10005735, Compound 31)
Affinity DataIC50: 7.40E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAMSH-like protease(Human)
California Institute of Technology

US Patent
LigandPNGBDBM401033(US10005735, Compound 31)
Affinity DataIC50: 170nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In DepthDetails
US Patent