BDBM401022 N-(3-((2R,5R)-6-amino-3,3,5-trifluoro-2,5-dimethyl-2,3,4,5-tetrahydropyridin-2-yl)-4-fluorophenyl)-5-(methoxy-d3)picolinamide::US10004738, 43

SMILES COc1ccc(nc1)C(=O)Nc1ccc(F)c(c1)[C@@]1(C)N=C(N)[C@](C)(F)CC1(F)F

InChI Key InChIKey=YWLRPFXPTFLZDK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401022   

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM401022(US10004738, 43 | N-(3-((2R,5R)-6-amino-3,3,5-trifl...)
Affinity DataKi:  91nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
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