BDBM400994 US10005735, Compound 7

SMILES Sc1cccc2cc(cnc12)C(=O)NCc1ccco1

InChI Key InChIKey=VRAJMQWHIOOSLH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 400994   

Target26S proteasome non-ATPase regulatory subunit 14(Human)
California Institute of Technology

US Patent
LigandPNGBDBM400994(US10005735, Compound 7)
Affinity DataIC50: 900nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCOP9 signalosome complex subunit 5(Human)
California Institute of Technology

US Patent
LigandPNGBDBM400994(US10005735, Compound 7)
Affinity DataIC50: 200nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAMSH-like protease(Human)
California Institute of Technology

US Patent
LigandPNGBDBM400994(US10005735, Compound 7)
Affinity DataIC50: 900nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In DepthDetails
US Patent