BDBM400048 N-(3-chloro-4-fluorophenyl)-7-(2-((3,3-difluoro-1-((3-methyl-1,1-dioxidothietan-3-yl)carbamoyl)cyclobutyl)amino)-2-oxoacetyl)-6-methyl-2,3-dihydro-1H-pyrrolizine-5-carboxamide ::US10328053, Compound 26::US10874640, Compound 26::US20230270719, Compound 26

SMILES Cc1c(C(=O)C(=O)NC2(CC2)c2c[nH]nn2)c2CCCn2c1C(=O)Nc1cc(F)c(F)c(F)c1

InChI Key InChIKey=USONUYOVXRBMND-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 400048   

TargetSodium/bile acid cotransporter(Human)
Gilead Sciences

US Patent
LigandPNGBDBM400048(US10328053, Compound 26 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  14.6nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCapsid protein(HBV-C)
Gilead Sciences

US Patent
LigandPNGBDBM400048(US10328053, Compound 26 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  14.6nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium/bile acid cotransporter(Human)
Gilead Sciences

US Patent
LigandPNGBDBM400048(US10328053, Compound 26 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  14.6nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In DepthDetails
US Patent