BDBM399936 US10323042, Example 16::US10738063, Example 16

SMILES Fc1cc(-c2c3OCCCn3nc2C(=O)NC2CC2)c(F)cc1Cl

InChI Key InChIKey=WYSBJUKHVQZOHC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 399936   

LigandPNGBDBM399936(US10323042, Example 16 | US10738063, Example 16)
Affinity DataIC50: 46nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM399936(US10323042, Example 16 | US10738063, Example 16)
Affinity DataIC50: 36.7nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM399936(US10323042, Example 16 | US10738063, Example 16)
Affinity DataIC50: 133nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM399936(US10323042, Example 16 | US10738063, Example 16)
Affinity DataIC50: 6.81E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM399936(US10323042, Example 16 | US10738063, Example 16)
Affinity DataIC50: 46nMAssay Description:Human PDE4B1 coding sequence (amino acids 122 to 736 from the sequence with accession number Q07343) with the mutations resulting in the amino acid s...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM399936(US10323042, Example 16 | US10738063, Example 16)
Affinity DataIC50: 36.7nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM399936(US10323042, Example 16 | US10738063, Example 16)
Affinity DataIC50: 133nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM399936(US10323042, Example 16 | US10738063, Example 16)
Affinity DataIC50: 6.81E+3nMAssay Description:A portion of the human PDE4D3 coding sequence (amino acids 50 to 672 from the sequence with accession number Q08499-2) was cloned into the baculoviru...More data for this Ligand-Target Pair
In DepthDetails
US Patent