BDBM399587 US10323036, Compound I-31::US10793574, Compound I-31

SMILES COc1c(Nc2cc(Nc3cc(ncn3)C#N)nc3[nH]n(C)c(=O)c23)cccc1-c1ncn(C)n1

InChI Key InChIKey=WZLPKFRYDJCCKJ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 399587   

TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399587(US10323036, Compound I-31 | US10793574, Compound I...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399587(US10323036, Compound I-31 | US10793574, Compound I...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent