BDBM398051 US10322118, Entry 9

SMILES Oc1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=ZSBDGXGICLIJGD-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 398051   

TargetPutative hydrolase(Pseudomonas aeruginosa (strain UCBPP-PA14))
Dartmouth College

US Patent
LigandPNGBDBM398051(US10322118, Entry 9)
Affinity DataIC50: 1.00E+5nMAssay Description:The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetOxysterols receptor LXR-beta(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM398051(US10322118, Entry 9)
Affinity DataEC50:  5.93E+5nMAssay Description:Agonist activity at recombinant human LXRbeta-LBD expressed in Escherichia coli BL21 (DE3) assessed as peptide D22 recruitment fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetApoptosis regulator BAX(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM398051(US10322118, Entry 9)
Affinity DataKd:  3.70E+4nMAssay Description:Binding affinity to BAX (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterols receptor LXR-beta(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM398051(US10322118, Entry 9)
Affinity DataKi:  6.20E+4nMAssay Description:Binding affinity to recombinant human LXRbeta-LBD expressed in Escherichia coli BL21 (DE3) assessed as inhibitory constant incubated for 30 mins by f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed