BDBM397957 US10604536, Compound 29::US9994590, Compound 29

SMILES [H][C@]1(C[C@@]1([H])c1nc2c(ccc3ncccc23)n1C)c1nc2c(C)ncc(C)n2n1

InChI Key InChIKey=NIPOUVRYTOUKCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397957   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sunovion Pharmaceuticals

US Patent
LigandPNGBDBM397957(US9994590, Compound 29 | US10604536, Compound 29)
Affinity DataIC50: 10nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details
Go to US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sunovion Pharmaceuticals

US Patent
LigandPNGBDBM397957(US9994590, Compound 29 | US10604536, Compound 29)
Affinity DataIC50: 10nMAssay Description:The compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 enzyme expressed in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2020
Entry Details
Go to US Patent