BDBM397410 US9987278, Compound Reference 20

SMILES CCCNc1nc(NCCc2ccncc2)ncc1C(=O)NCCC(CC)NC(=O)CN(C)C(=O)\C=C\CN(C)C

InChI Key InChIKey=IIEMKEYRHQKQHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 397410   

LigandPNGBDBM397410(US9987278, Compound Reference 20)
Affinity DataIC50: 1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
Go to US Patent