BDBM392816 5-Fluoro-2-((4-oxo-2-(pyridin-4-yl)-3-(thiophen-2-yl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-1-yl)methyl)benzonitrile::US10301306, Example 14::US10301306, Example 144

SMILES Fc1ccc(Cn2c3CCNC(=O)c3c(-c3cccs3)c2-c2ccncc2)c(c1)C#N

InChI Key InChIKey=KAFYAWKHQWJZHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392816   

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM392816(5-Fluoro-2-((4-oxo-2-(pyridin-4-yl)-3-(thiophen-2-...)
Affinity DataIC50: 30nMAssay Description:The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM392816(5-Fluoro-2-((4-oxo-2-(pyridin-4-yl)-3-(thiophen-2-...)
Affinity DataIC50: 30nMAssay Description:The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent