BDBM389915 1-(4-{5-[3-(4-Fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]pyridin-2-yl}piperazin-1-yl)ethan-1-one::US10766897, Compound 86::US10968223, Compound 86::US9951068, Compound 86

SMILES CC(=O)N1CCN(CC1)c1ccc(cn1)-c1nc2ccncc2n1-c1ccc(F)cc1

InChI Key InChIKey=KOEISVHAQNJVEX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 389915   

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389915(US9951068, Compound 86 | 1-(4-{5-[3-(4-Fluoropheny...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

LigandPNGBDBM389915(US9951068, Compound 86 | 1-(4-{5-[3-(4-Fluoropheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Electrophysiological recordings were made from a Chinese Hamster Lung cell line stably expressing the full length hERG channel. Single cell ion curre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389915(US9951068, Compound 86 | 1-(4-{5-[3-(4-Fluoropheny...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

LigandPNGBDBM389915(US9951068, Compound 86 | 1-(4-{5-[3-(4-Fluoropheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389915(US9951068, Compound 86 | 1-(4-{5-[3-(4-Fluoropheny...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent

LigandPNGBDBM389915(US9951068, Compound 86 | 1-(4-{5-[3-(4-Fluoropheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:hERG: Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389915(US9951068, Compound 86 | 1-(4-{5-[3-(4-Fluoropheny...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent