BDBM389912 5-[3-(4-Chloro-2-fluorophenyl)- 3H-imidazo[4,5-c]pyridin-2-yl]- 2-(pyrrolidin-1-yl)pyrimidine::US10766897, Compound 83::US10968223, Compound 83::US9951068, Compound 83

SMILES Fc1cc(Cl)ccc1-n1c(nc2ccncc12)-c1cnc(nc1)N1CCCC1

InChI Key InChIKey=LFRSKDPEJXMRLF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 389912   

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389912(US9951068, Compound 83 | 5-[3-(4-Chloro-2-fluoroph...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389912(US9951068, Compound 83 | 5-[3-(4-Chloro-2-fluoroph...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389912(US9951068, Compound 83 | 5-[3-(4-Chloro-2-fluoroph...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389912(US9951068, Compound 83 | 5-[3-(4-Chloro-2-fluoroph...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent