BDBM389853 4-{5-[3-(4-Fluorophenyl)-3H- imidazo[4,5-c]pyridin-2- yl]pyrimidin-2-yl}-1,4- oxazepane::US10766897, Compound 25::US10968223, Compound 25::US9951068, Compound 25

SMILES Fc1ccc(cc1)-n1c(nc2ccncc12)-c1cnc(nc1)N1CCCOCC1

InChI Key InChIKey=NQJNFBPJUXWNDE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 389853   

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389853(US9951068, Compound 25 | 4-{5-[3-(4-Fluorophenyl)-...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389853(US9951068, Compound 25 | 4-{5-[3-(4-Fluorophenyl)-...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389853(US9951068, Compound 25 | 4-{5-[3-(4-Fluorophenyl)-...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389853(US9951068, Compound 25 | 4-{5-[3-(4-Fluorophenyl)-...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent