BDBM389851 (2R,6S)-4-{5-[3-(4- Fluorophenyl)-3H-imidazo[4,5- c]pyridin-2-yl]pyrimidin-2-yl}- 2,6-dimethylmorpholine::US10766897, Compound 23::US10968223, Compound 23::US9951068, Compound 23

SMILES C[C@H]1CN(C[C@@H](C)O1)c1ncc(cn1)-c1nc2ccncc2n1-c1ccc(F)cc1

InChI Key InChIKey=FBLXPLWOASVECE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 389851   

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389851(US9951068, Compound 23 | (2R,6S)-4-{5-[3-(4- Fluor...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

LigandPNGBDBM389851(US9951068, Compound 23 | (2R,6S)-4-{5-[3-(4- Fluor...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389851(US9951068, Compound 23 | (2R,6S)-4-{5-[3-(4- Fluor...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

LigandPNGBDBM389851(US9951068, Compound 23 | (2R,6S)-4-{5-[3-(4- Fluor...)
Affinity DataIC50: 1.00E+4nMAssay Description:Electrophysiological recordings were made from a Chinese Hamster Lung cell line stably expressing the full length hERG channel. Single cell ion curre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389851(US9951068, Compound 23 | (2R,6S)-4-{5-[3-(4- Fluor...)
Affinity DataIC50: 50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent

LigandPNGBDBM389851(US9951068, Compound 23 | (2R,6S)-4-{5-[3-(4- Fluor...)
Affinity DataIC50: 1.00E+4nMAssay Description:hERG: Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM389851(US9951068, Compound 23 | (2R,6S)-4-{5-[3-(4- Fluor...)
Affinity DataIC50: 50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent