BDBM389731 1-{(R)-4-[2-(2-Dimethylamino-pyrimidin-5-yl)-5-trifluoromethyl-1,2,3,4-tetrahydro-isoquinolin-8-yl]-2-methyl-piperazin-1-yl}-2-(3,5-dimethyl-[1,2,4]triazol-1-yl)-ethanone::US9951063, 50

SMILES C[C@@H]1CN(CCN1C(=O)Cn1nc(C)nc1C)c1ccc(c2CCN(Cc12)c1cnc(nc1)N(C)C)C(F)(F)F

InChI Key InChIKey=PWUVTVGZKZNWFB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 389731   

TargetC-X-C chemokine receptor type 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM389731(US9951063, 50 | 1-{(R)-4-[2-(2-Dimethylamino-pyrim...)
Affinity DataIC50: 2.26nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
Go to US Patent