BDBM388706 N-[1-(Methoxymethyl)cyclobutyl]-4-[3-(1-quinolin-6-ylcyclopropyl)imidazo[1,2-a]pyrimidin-6-yl]benzamide::US11261191, Example 36::US9944645, 36

SMILES COCC1(CCC1)NC(=O)c1ccc(cc1)-c1cnc2ncc(n2c1)C1(CC1)c1ccc2ncccc2c1

InChI Key InChIKey=DSHIHZALYPYUBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 388706   

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM388706(N-[1-(Methoxymethyl)cyclobutyl]-4-[3-(1-quinolin-6...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM388706(N-[1-(Methoxymethyl)cyclobutyl]-4-[3-(1-quinolin-6...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
Go to US Patent