BDBM388663 2-chloro-N-methyl-4-[3-(quinolin-6-yloxy)imidazo[1,2-a]pyrimidin-6-yl]benzamide::US11261191, Example 17::US9944645, 17

SMILES CNC(=O)c1ccc(cc1Cl)-c1cnc2ncc(Oc3ccc4ncccc4c3)n2c1

InChI Key InChIKey=AJCHYDXTULVLRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 388663   

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM388663(2-chloro-N-methyl-4-[3-(quinolin-6-yloxy)imidazo[1...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM388663(2-chloro-N-methyl-4-[3-(quinolin-6-yloxy)imidazo[1...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
Go to US Patent