BDBM388660 2-(4-Bromo-3-fluorophenyl)-7-(4-methoxyphenoxy)imidazo[1,2-b][1,2,4]triazine::US11261191, Example 14::US9944645, 14

SMILES COc1ccc(Oc2cnc3ncc(nn23)-c2ccc(Br)c(F)c2)cc1

InChI Key InChIKey=UOXGAQFTZAHFAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 388660   

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM388660(2-(4-Bromo-3-fluorophenyl)-7-(4-methoxyphenoxy)imi...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM388660(2-(4-Bromo-3-fluorophenyl)-7-(4-methoxyphenoxy)imi...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
Go to US Patent