BDBM388466 (1aR,5aR)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid ((S)-1-methoxycarbamoyl-2,2-dimethyl-propyl)-amide::US9944606, Compound 755

SMILES CONC(=O)[C@@H](NC(=O)c1nn(c2[C@@H]3C[C@@H]3Cc12)-c1c[n+]([O-])ccn1)C(C)(C)C

InChI Key InChIKey=LDQNXKKJIIMJDQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 388466   

TargetCannabinoid receptor 2(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM388466(US9944606, Compound 755 | (1aR,5aR)-2-(4-Oxy-pyraz...)
Affinity DataKi:  3.80nMAssay Description:Preparation of Membranes: HEK293 cells stably expressing human CB2 receptor were collected, washed in ice cold PBS, and centrifuged at 48,000×g for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM388466(US9944606, Compound 755 | (1aR,5aR)-2-(4-Oxy-pyraz...)
Affinity DataKi:  1.20E+3nMAssay Description:Preparation of Membranes: HEK293 cells stably expressing human CB2 receptor were collected, washed in ice cold PBS, and centrifuged at 48,000×g for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent