BDBM386097 US10287305, Example 37::US10508083, Example 37::US11292766, Example 37::cis-3-((ethylsulfonyl)amino)-2- (((cis-4- methylcyclohexyl)oxy)methyl)-N- phenylpiperidine-1-carboxamide

SMILES CCS(=O)(=O)N[C@H]1CCCN([C@H]1CO[C@@H]1CC[C@H](C)CC1)C(=O)Nc1ccccc1

InChI Key InChIKey=FRZSBOLMXFUBOY-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 386097   

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386097(cis-3-((ethylsulfonyl)amino)-2- (((cis-4- methylcy...)
Affinity DataEC50:  880nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386097(cis-3-((ethylsulfonyl)amino)-2- (((cis-4- methylcy...)
Affinity DataEC50:  880nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386097(cis-3-((ethylsulfonyl)amino)-2- (((cis-4- methylcy...)
Affinity DataEC50:  880nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
Go to US Patent