BDBM386085 N-((2R,3S)-2-(((cis-4-(2- methoxyphenyl)cyclohexyl)oxy)- methyl)piperidin-3- yl)methanesulfonamide::US10287305, Example 27::US10508083, Example 27::US11292766, Example 27

SMILES COc1ccccc1[C@@H]1CC[C@@H](CC1)OC[C@@H]1NCCC[C@@H]1NS(C)(=O)=O

InChI Key InChIKey=FJHULEFVSHHNCH-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 386085   

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386085(N-((2R,3S)-2-(((cis-4-(2- methoxyphenyl)cyclohexyl...)
Affinity DataEC50:  310nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
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TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386085(N-((2R,3S)-2-(((cis-4-(2- methoxyphenyl)cyclohexyl...)
Affinity DataEC50:  310nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386085(N-((2R,3S)-2-(((cis-4-(2- methoxyphenyl)cyclohexyl...)
Affinity DataEC50:  310nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
Go to US Patent