BDBM385037 (S)-3-(5-(5-((2H-tetrazol-5-yl)methyl)-2-methoxybenzyl)-2-amino-6-((1-(methylthio)-heptan-3-yl)amino)pyrimidin-4-yl)propanoic acid ::US10287253, Example 48

SMILES CCCC[C@@H](CCSC)Nc1nc(N)nc(CCC(O)=O)c1Cc1cc(Cc2nn[nH]n2)ccc1OC

InChI Key InChIKey=CTQMENXAVCFTSG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385037   

TargetToll-like receptor 7(Human)
Apros Therapeutics

US Patent
LigandPNGBDBM385037((S)-3-(5-(5-((2H-tetrazol-5-yl)methyl)-2-methoxybe...)
Affinity DataEC50: <100nMAssay Description:HEK-Blue TLR7 cells were purchased from Invivogen (San Diego, Calif.). The following description was taken from the product information sheet."HEK-Bl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent