BDBM385025 (S)—N4-(1-(2H-tetrazol-5-yl)heptan-3-yl)-S-(2-methoxybenzyl)-6-methylpyrimidine-2,4-diamine ::US10287253, Example 36

SMILES CCCC[C@@H](CCc1nn[nH]n1)Nc1nc(N)nc(C)c1Cc1ccccc1OC

InChI Key InChIKey=KNKIBECPMRCOCL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385025   

TargetToll-like receptor 7(Human)
Apros Therapeutics

US Patent
LigandPNGBDBM385025((S)—N4-(1-(2H-tetrazol-5-yl)heptan-3-yl)-S-(2...)
Affinity DataEC50:  550nMAssay Description:HEK-Blue TLR7 cells were purchased from Invivogen (San Diego, Calif.). The following description was taken from the product information sheet."HEK-Bl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent