BDBM385016 (S)-3-(2-amino-6-((1-hydroxyheptan-3-yl)amino)-5-(2-methoxybenzyl)-pyrimidin-4-yl)propanoic acid ::US10287253, Example 27::US10287253, Example 28

SMILES CCCC[C@@H](CCO)Nc1nc(N)nc(CCC(O)=O)c1Cc1ccccc1OC

InChI Key InChIKey=CQDBENQSYWSWGM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 385016   

TargetToll-like receptor 7(Human)
Apros Therapeutics

US Patent
LigandPNGBDBM385016(US10287253, Example 28 | (S)-3-(2-amino-6-((1-hydr...)
Affinity DataEC50:  550nMAssay Description:HEK-Blue TLR7 cells were purchased from Invivogen (San Diego, Calif.). The following description was taken from the product information sheet."HEK-Bl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Apros Therapeutics

US Patent
LigandPNGBDBM385016(US10287253, Example 28 | (S)-3-(2-amino-6-((1-hydr...)
Affinity DataEC50:  5.50E+3nMAssay Description:HEK-Blue TLR7 cells were purchased from Invivogen (San Diego, Calif.). The following description was taken from the product information sheet."HEK-Bl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent