BDBM385001 5-(5-(1-(2H-tetrazol-5-yl)cyclopropyl)-2-methoxybenzyl)-N4-butyl-6-methylpyrimidine-2,4-diamine ::US10287253, Example 13

SMILES CCCCNc1nc(N)nc(C)c1Cc1cc(ccc1OC)C1(CC1)c1nn[nH]n1

InChI Key InChIKey=SCCTZCLCGYDZLR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385001   

TargetToll-like receptor 7(Human)
Apros Therapeutics

US Patent
LigandPNGBDBM385001(5-(5-(1-(2H-tetrazol-5-yl)cyclopropyl)-2-methoxybe...)
Affinity DataEC50:  550nMAssay Description:HEK-Blue TLR7 cells were purchased from Invivogen (San Diego, Calif.). The following description was taken from the product information sheet."HEK-Bl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent