BDBM384639 4-[(trans-4-{4-[(2S)- tetrahydrofuran-2- ylcarbonyl]piperazin-1- yl}cyclohexyl)amino] quinazoline-6-carbonitrile::US9932350, 6-11

SMILES O=C([C@@H]1CCCO1)N1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)C#N

InChI Key InChIKey=OHETZTXTIFMYSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384639   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384639(US9932350, 6-11 | 4-[(trans-4-{4-[(2S)- tetrahydro...)
Affinity DataIC50: 11nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In DepthDetails
US Patent