BDBM384611 4-({trans-4-[(3R or 3S)- 3-(morpholin-4- ylmethyl)piperidin-1- yl]cyclohexyl}amino) quinazoline-6-carbonitrile::US9932350, 3-41::US9932350, 3-42

SMILES N#Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCCC(CN4CCOCC4)C3)c2c1

InChI Key InChIKey=HJTYFGKDVYFWRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 384611   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384611(US9932350, 3-42 | 4-({trans-4-[(3R or 3S)- 3-(morp...)
Affinity DataIC50: 70nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384611(US9932350, 3-42 | 4-({trans-4-[(3R or 3S)- 3-(morp...)
Affinity DataIC50: 5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In DepthDetails
US Patent