BDBM384204 4-(6-(4-(Aminomethyl)-4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-b]pyrazin-3-yl)-3-methylpyridin-2-amine::US10280171, Example 124::US10851110, Example 124::US11466017, Example 124
SMILES Cc1c(N)nccc1-c1n[nH]c2nc(cnc12)N1CCC(C)(CN)CC1
InChI Key InChIKey=LLWQCPSJCBXVHN-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 384204
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 377nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 377nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Human)
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 377nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair