BDBM384090 US10280167, Example 15

SMILES Nc1nc(nc2n(Cc3ccccc3)c(=O)[nH]c12)-c1cncnc1

InChI Key InChIKey=WMZBESXWTUMERC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384090   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM384090(US10280167, Example 15)
Affinity DataEC50:  1.69E+4nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent